Spider-Manis everyone’s favorite neighborhood superhero whose origin story is something that fans are quite familiar with. After a radioactive spider bites a nerd who has no strength to boast of, Peter Parker transforms into a hero with the resilience and wall-crawling abilities of a spider.Spider-Manswings into action and saves the people of New York from crime whenever his Spider Senses tingle in the pages of Marvel comics.

Spider-Man is easily one of the most popular Marvel superheroes of all time and boasts way more strength than most people would assume. However, some enemies can still best him in battle, with some of DC’s most iconic villains being more than enough to subject this superhero to a hellacious beatdown.There are many versions of the webhead, but the powers of the Amazing Spider-Man will be taken into consideration for these battles against the wide library of DC Comics' foes.

5Poison Ivy

Her Supernatural Control Over Plants Can Reach Ridiculous Extents Of Power

Batman has a suite of iconic villains who are a joy to interact with courtesy of the sheer charisma they exude when they get the time to shine. Poison Ivy is a great example of the same, captivating fans as she uses her plant powers to try and trap Batman. Despite not seeming like the strongest villain that Batman has faced, there are times when Poison Ivy’s powers can magnify in strength out of nowhere to surprise anyone underestimating her.

It’s easy to see whySpider-Man may find it trickyto escape her vines and plants as they try to constrict her. If this isn’t tricky enough as is, then Poison Ivy can also use mind-controlling pheromones to sway people to do her bidding. This can be a major problem for Peter, who will lose this battle automatically if he falls prey to Poison Ivy’s mind-control powers.

4Brainiac

His Mind-Control Powers And Superior Intellect Make Him The Clear Victor Over Spider-Man

Throughout many iterations, this malevolent cyborg was able to place all of the Justice League under his control. He has been both knowledge keeper, collector, and universal conqueror, and his sights have been set on the multiverse for quite some time.

Even ifhe prepares extensively for this encounter, there’s no way Spider-Man can fight this foe for too long before incurring serious injuries. Brainiac can take over Peter’s mind, overwhelm him with powerful hypnotized goons, or just use the strength he possesses to beat Spider-Man viciously. The suite of options at his behest is impressive and shows why Spider-Man has no chance of defeating Brainiac.

3Ares

His Olympian Superiority Ensures That Spider-Man Will Be Ragdolled By This God

There are many tough foes that Spider-Man has taken on, using his resilience and willpower to come out victorious after a brutal battle. However, even a hero as dogged as this webhead won’t be able to overcome his physical limitations when fighting against literal gods, This is whyan encounter against Areswill result in a one-sided beatdown that no one wants to subject their friendly neighborhood superhero to.

This Olympian god is ridiculously strong, and one punch from this villain will be enough to take Spider-Man out. Given his stature as the war god, it’s easy to see why hateful and violent energy fuels his bloodlust even more, letting him recover from serious wounds and enhance his power to greater heights. All of these abilities ensure that Spider-Man has no chance of landing a single punch on Ares, let alone defeating him in a one-on-one confrontation, so it’s best to leave this foe to Wonder Woman.

2Amazo

He Can Mimic The Powers Of His Strongest Foes To Destroy His Enemies

It takes an amazing technical marvel to replicate the powers of heroes like Superman and the Flash, making it easy to see whyAmazo is one of the strongest DC supervillainsof all time. He may not seem like much, but his ability to mimic his opponents' powers means that anyone who fights against Amazo will be in for a lengthy and evenly-fought scenario. Such is the case if Spider-Man goes toe-to-toe against this villain, and that’s the best-case scenario.

If Amazo has stored the data of all the heroes he’s fought before encountering Spider-Man, then Peter Parker has no chance of coming out victorious against this super-powered android. He can channel the power of ultra-powerful beings to smash Spider-Man with a single punch, treating him like a bug as he squashes the webhead and moves on to bigger threats.

1Doomsday

A Villain Who Can Kill Superman And Becomes Stronger With Each Death

Anyone even remotely familiar with Doomsday knows why this supervillain can kill Spider-Man. After all, not many beings can bring the fight to Superman, let alone kill him. His rocky and demonic appearance showcasesa monster that only grows in strengthwith each death.

So, the full-powered version of this villain will destroy Spider-Man with the greatest of ease. Even if the webhead teams up with other superheroes to take out this villain, he needs to be careful and not put himself in harm’s way for too long if he doesn’t want to be obliterated with a single hit.